How long does Prozac stay in your system?
Prozac (fluoxetine) stays in your body for five to six weeks after the last capsule. Sexual side effects can outlast it. That is called PSSD.
SIDEfxHUB is a patient charity. We are not health professionals, and this does not replace medical advice. Don't start, stop or change any medicine because of what you read here. Talk to your doctor first.
If you are in crisis:116 123 Samaritans (UK)988 Lifeline (US)Find a helpline
Prozac (fluoxetine) stays in your body for five to six weeks after your last capsule, says the UK information for doctors. Sexual side effects can last longer than the drug. The UK leaflet warns they have sometimes carried on after stopping, and then it’s called post-SSRI sexual dysfunction (PSSD).
If you stopped a few weeks ago, some of it is still in you. If it’s been months, those figures say it has gone. There’s no reason to wait for it to wash out before you tell your GP what has changed.
PSSD isn’t only about sex, even though the name says so. The checklist doctors and researchers proposed in 2022 to recognise it has one sign every case needs: a lasting change in how the genitals feel, often numbness. It also lists emotional numbing, problems with concentration and memory, and changes in other senses.
The story in 3 lines
- Fluoxetine stays in the body for five to six weeks after the last capsule (UK information for doctors).
- The UK leaflet says sexual problems have in some cases “continued after stopping treatment”. Prozac’s US label has said they “occasionally persist” since 2011.
- No reliable figure exists for how often (2023 review). Patients call it PSSD.
Press: contact@sidefxhub.com
Katie was 21 when she was prescribed Prozac, an SSRI antidepressant, and she took it for about three years. Her sexual and emotional problems didn’t stop when the capsules did. In this short clip she describes going back to her GP. Watch it if you’ve been told it must be something else.
At that point, she says, she still didn’t know the medicine was behind it. Her doctors pointed to low self-esteem, trauma and depression. She’d had low confidence and trauma before fluoxetine too, she says, but no problems with sex, attraction or feeling close to someone. “Before SSRIs, I experienced these very normally.”
What is Prozac’s half-life?
About four to six days, if you take it every day. That’s how long it takes for the amount in your blood to drop by half. After one half-life, half is left. After two, a quarter.
There’s a second clock. Your liver turns fluoxetine into norfluoxetine, another substance that also acts on the body. It can take up to 16 days to halve. Together, says the UK information for doctors, the two keep the drug in your body for five to six weeks. If you have liver disease, both take longer to halve.
You can see this in your own leaflet. The UK fluoxetine leaflet says not to take a certain older type of antidepressant, called an MAOI, for at least five weeks after you stop fluoxetine. After a long or high-dose course, it adds, your doctor may need to wait longer. That gap is there because fluoxetine is still in your body, and the two could clash.
Is Prozac still in your brain after you stop?
For the first few days, mostly yes. Then it seems to leave your brain about as fast as it leaves your blood.
Fluoxetine contains fluorine, which a special MRI scan can pick up in a living brain.
In a small US study, people on daily fluoxetine switched to dummy pills for three days. On average, nearly 9 in 10 of the signal from fluoxetine, and what the body makes from it, was still showing up in their brains. With paroxetine, another SSRI, it was about 4 in 10.
For what happens after that, a French team scanned just two people after they stopped. Overall, the drug faded from brain and blood at about the same pace. A scan shows whether the drug is there. It can’t show why symptoms might stay once it has gone.
Why do side effects last after Prozac is out of your system?
The cause isn’t known yet, a 2022 review says. But the UK leaflet does warn about it. Medicines like fluoxetine may cause sexual problems, it says, and adds: “In some cases, these symptoms have continued after stopping treatment.” It gives no end date. Our article on Prozac’s sexual side effects covers how common they are.
The 2022 checklist says ordinary sexual side effects can linger for days or weeks after the last dose. Once problems have lasted three months, it says, PSSD is more likely. That’s more than twice as long as even fluoxetine takes to leave your body.
Two clocks after your last fluoxetine capsule
For some people it has lasted years after stopping. Nobody knows yet who will be affected, or whether it will ease.
What can I do?
These medicines help many people. If you have side effects, that’s a decision for you and your prescriber. Don’t stop suddenly. Fluoxetine’s slow exit doesn’t change that: the leaflet says not to stop without asking your doctor, and lists withdrawal effects such as dizziness and pins and needles. Our page on withdrawal or PSSD explains the difference.
With fluoxetine the weeks since your last capsule matter, so write your dates down for your GP: “Fluoxetine 20 mg from May 2024, last capsule 2 February 2026. May 2026: genitals still numb, and I feel emotionally flat.”
What to say to your GP
You could open with: “My last fluoxetine capsule was [number] months ago. The leaflet says sexual problems can continue after stopping, and mine have.”
- Could this still be fluoxetine in my system, this long after?
- What else should we rule out?
- Can you note my dates and symptoms, including the ones that aren't sexual?
- Will you report it to the Yellow Card scheme, or shall I?
Many people say it took time to be taken seriously. Bring the leaflet line. You can report it without a doctor agreeing.
Report it: it helps everyone
A doctor’s note helps you. A report to the medicines regulator helps everyone else: it is how patterns get noticed.
- No proof needed. A suspicion is enough, even years after stopping.
- Where: the Yellow Card scheme in the UK, MedWatch in the US.
- Use the right words. If symptoms continued after stopping, write Post-SSRI sexual dysfunction (MedDRA 10086208).
Our reporting guide walks you through it
What else do people ask?
How long does one Prozac capsule stay in your system? Not as long as after months of daily use. Prozac’s US label gives fluoxetine a shorter half-life after a single dose, but norfluoxetine still halves just as slowly. Lasting problems have been reported after short courses too: see PSSD after a few pills.
Is it the same for other antidepressants? Not for sertraline. Its half-life is about a day, so it clears much faster. Many UK antidepressant leaflets carry the same warning about sexual problems continuing after stopping: see which antidepressants are linked to PSSD.
When was this first reported? In 1991, for fluoxetine. That’s when the UK medicines regulator had its first reports of sexual problems that continued after someone stopped it, says the 2022 checklist paper.
Katie has lived with this for about 14 years, and only linked it to fluoxetine last year. If you’re counting weeks rather than years, you don’t have to wait for anything to clear before you report it. Our page on post-SSRI sexual dysfunction explains what is known.
Sources
- Fluoxetine 20 mg hard capsules, summary of product characteristics (UK information for doctors), Brown & Burk UK Ltd, Electronic Medicines Compendium (EMC 15755), text revised 28 September 2022. Section 5.2: “The elimination half-life of fluoxetine is 4 to 6 days and for norfluoxetine 4 to16 days. These long half-lives are responsible for persistence of the drug for 5-6 weeks after discontinuation.” Norfluoxetine is “the active metabolite”. In liver disease (alcoholic cirrhosis) the half-lives rise to 7 and 12 days. Section 4.2: “When dosing is stopped, active drug substances will persist in the body for weeks.” Section 4.4: “There have been reports of long-lasting sexual dysfunction where the symptoms have continued despite discontinuation of SSRIs”. The same section asks for at least 5 weeks between stopping fluoxetine and starting an irreversible, non-selective MAOI. Section 4.5: the long half-lives “should be borne in mind” when considering interactions, “e.g. when switching from fluoxetine to other antidepressants”. Section 4.8, footnote 16: sexual problems “occasionally persisting after treatment discontinuation”.
- Fluoxetine 20 mg hard capsules, patient leaflet, Brown & Burk UK Ltd, EMC 15755, last revised September 2022. Section 2, under “Sexual dysfunction”, says SSRIs “may cause symptoms of sexual dysfunction”, and: “In some cases, these symptoms have continued after stopping treatment”. Section 2 also says not to take irreversible, non-selective MAOIs “for at least 5 weeks after you stop taking Fluoxetine”. After a long or high-dose course, “a longer interval needs to be considered by your doctor”. Section 3: “Do not stop taking Fluoxetine without asking your doctor first”; withdrawal effects include dizziness and “tingling feelings like pins and needles”.
- Prozac (fluoxetine), US prescribing information, revised August 2023. DailyMed, US National Library of Medicine. Section 12.3: fluoxetine elimination half-life “of 1 to 3 days after acute administration and 4 to 6 days after chronic administration”; norfluoxetine “4 to 16 days after acute and chronic administration”. Section 6.1: “Symptoms of sexual dysfunction occasionally persist after discontinuation of fluoxetine treatment.”
- US Food and Drug Administration, supplement approval letter, NDA 18-936/S-096 and 21-235/S-018, signed 15 June 2011. Approves text added to section 6.1 “related to occasional persistence of sexual dysfunction following discontinuation of fluoxetine treatment”. Eli Lilly’s application was dated 8 April 2011.
- Healy D, Bahrick A, Bak M and colleagues. Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin. Int J Risk Saf Med 2022;33(1):65-76. Criteria proposed by an expert panel. Section 3, necessary criterion: “An enduring change in somatic (tactile) or erogenous (sexual) genital sensation after treatment stops”. Ancillary symptoms include “emotional numbing”, “other sensory problems” and “cognitive impairment”. Section 3 also: “The sexual dysfunction that accompanies normal antidepressant use may linger for some days or weeks following discontinuation of treatment. The present consensus is that once dysfunction lasts for three months, it is more likely to be PSSD.” The paper does not discuss fluoxetine’s half-life. Introduction: the MHRA “indicated that their first reports of a sexual dysfunction that continued after an SSRI was withdrawn involved fluvoxamine in 1987 and fluoxetine in 1991”.
- Tarchi L, Merola GP, Baccaredda-Boy O and colleagues. Selective serotonin reuptake inhibitors, post-treatment sexual dysfunction and persistent genital arousal disorder: a systematic review. Pharmacoepidemiol Drug Saf 2023;32(10):1053-67. Abstract: “It was not possible to determine reliable estimates of prevalence.”
- Henry ME, Moore CM, Kaufman MJ and colleagues. Brain kinetics of paroxetine and fluoxetine on the third day of placebo substitution: a fluorine MRS study. Am J Psychiatry 2000;157(9):1506-8. Eight people with depression in remission, on 20 mg a day of fluoxetine or paroxetine, were given placebo for three days. Of the brain fluorine signal from fluoxetine (plus fluorinated metabolites), “a mean of 88% (SD=13%)” remained, “compared with a mean of 38% (SD=17%)” for paroxetine. Read as an abstract only.
- Bolo NR, Hodé Y, Nédélec JF and colleagues. Brain pharmacokinetics and tissue distribution in vivo of fluvoxamine and fluoxetine by fluorine magnetic resonance spectroscopy. Neuropsychopharmacology 2000;23(4):428-38. France. Brain-to-plasma half-life ratio for fluoxetine plus norfluoxetine 1.0 (two people). Read as an abstract only.
- Peleg LC, Rabinovitch D, Lavie Y and colleagues. Post-SSRI sexual dysfunction (PSSD): biological plausibility, symptoms, diagnosis, and presumed risk factors. Sex Med Rev 2022;10(1):91-98. Abstract: the “underlying neurobiological mechanisms” of PSSD “are unclear”.
- Lustral (sertraline), UK summary of product characteristics, EMC 1070, section 5.2: “The mean half-life of sertraline is approximately 26 hours”.
- Moral Medicine, I Lost My Sexual Identity After Prozac, interview with Katie, published 26 May 2026, ten minutes, quoted from YouTube’s automatic captions. Prescribed fluoxetine at 21, about three years, at 0:40 to 0:51. Going back to her GP after stopping, and what doctors said, at 4:40 to 4:58. Low confidence and trauma before fluoxetine, but no problems “with sex, attraction, or emotional connection”, at 4:58 to 5:09; “Before SSRIs, I experienced these very normally”, at 5:11. Realised only “last year” that antidepressants were the cause, at 0:52; symptoms for 14 years at 6:11. Embedded from 4:40 to 5:16.
- Image: Vaccinationist, Fluoxetine.svg, public domain, via Wikimedia Commons, served from this site.
- MedDRA term and code: Post-SSRI sexual dysfunction, 10086208 (
meddra.ts).
Sources checked on 28 October 2026. AI-assisted writing and review, not clinical review.
This information does not replace medical advice. Talk to your doctor before you make any decision about your treatment.
640+ people have joined the registry.
Join them, then report your side effects.
Free. Sign up takes 2 minutes.
Fluoxetine: what the official texts say, country by country
For the SSRI antidepressant fluoxetine (Prozac), the product information we read in the United Kingdom, that of a generic product, says there have been reports of long-lasting sexual dysfunction where symptoms continued after SSRIs were stopped. This is known as post-SSRI sexual dysfunction (PSSD). The EU medicines regulator set the wording of this warning in 2019 for ten medicines, fluoxetine among them, and a government answer in Parliament says UK product information for all SSRIs was updated in 2019 to carry it. In the United States, the Prozac text for professionals says that symptoms of sexual dysfunction occasionally persist after fluoxetine is stopped. That sentence stands in the section on adverse reactions, not in a warning, and not every fluoxetine label there has it.
This is a record of what each text says and of the date it prints. A text is quoted in its own words, or summarised where the row says so. It is not a comparison of countries. All medicines and countries
Fluoxetine: the official texts, country by country (36 texts read)
| Country or region | What the text says | Document | Dates |
|---|---|---|---|
| United Kingdom | Sexual side effects that continue after stopping4.4 Special warnings and precautions for use · Sexual dysfunction Sexual side effects, as listed4.8 Undesirable effects · b) Tabulated list of adverse reactions · Psychiatric disorders · Common Sexual side effects, as listed4.8 Undesirable effects · b) Tabulated list of adverse reactions · Psychiatric disorders · Uncommon Sexual side effects, as listed4.8 Undesirable effects · b) Tabulated list of adverse reactions · Reproductive system and breast disorders · Common Sexual side effects, as listed4.8 Undesirable effects · b) Tabulated list of adverse reactions · Reproductive system and breast disorders · Uncommon Sexual side effects that continue after stopping4.8 Undesirable effects · b) Tabulated list of adverse reactions · footnote 16 Sexual side effects, as listed4.8 Undesirable effects · b) Tabulated list of adverse reactions · Reproductive system and breast disorders · Rare The same text also says4.8 Undesirable effects · a) Summary of the safety profile Sexual side effects, as listed4.8 Undesirable effects · d) Paediatric population The originator product is not in the list we read. This is another product from that list. Texts for other products in this country do not all say the same. We searched them for sentences about sexual side effects continuing after stopping and did not read them whole. This row shows the product named, and no other. A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals Summary of Product Characteristics (SmPC): Fluoxetine 10 mg hard capsulesFluoxetine 10 mg hard capsules, Brown & Burk UK Ltd · Read in a compendium of product information: emcAlso on record: patients' leaflet, with such a sentence; 3 related documents, with such a sentence | Text revisedChecked |
| European Union | Sexual side effects that continue after stopping3. Serotonin and noradrenaline reuptake inhibitors (SNRI); selective serotonin reuptake inhibitors (SSRI) – Persistent sexual dysfunction after drug withdrawal (EPITT no 19277) · Summary of product characteristics · 4.4. Special warnings and precautions for use · Sexual dysfunction Sexual side effects that continue after stopping3. Serotonin and noradrenaline reuptake inhibitors (SNRI); selective serotonin reuptake inhibitors (SSRI) – Persistent sexual dysfunction after drug withdrawal (EPITT no 19277) · Package leaflet · 2. What you need to know before you take [Invented name] · Warnings and precautions The wording is for ten medicines: citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, desvenlafaxine, duloxetine, milnacipran and venlafaxine. This is wording for national product texts. There is no single EU product text for this medicine. | Document from the regulator New product information wording – Extracts from PRAC recommendations on signals. Adopted at the 13-16 May 2019 PRACRead on the regulator's site: European Medicines AgencyAlso on record: 1 more related document, with such a sentence | PublishedChecked |
| United States | Sexual side effects, as listed5 WARNINGS AND PRECAUTIONS · 5.17 Sexual Dysfunction The same text also says5 WARNINGS AND PRECAUTIONS · 5.17 Sexual Dysfunction Sexual side effects that continue after stopping6 ADVERSE REACTIONS · 6.1 Clinical Trials Experience · Male and female sexual dysfunction with SSRIs The same text also says6 ADVERSE REACTIONS · 6.1 Clinical Trials Experience · Male and female sexual dysfunction with SSRIs The date given is for this product. Texts for other products carry other dates. An official list of medicines we read shows this product as discontinued or no longer marketed, and the text in this row is still this product's own. This text names sexual side effects in several places that this row does not show. Together those passages are too long to reproduce here. The document link in this row opens the text. That they are not shown says nothing about how common these side effects are. On 14 October 2026 we searched the labels in openFDA, the FDA's open database. The sentence about sexual dysfunction persisting after stopping, which this row shows, stood on 388 of the 439 labels in that database that contain fluoxetine. Five of the 388 are labels of the combination of olanzapine with fluoxetine. On those 388 labels the sentence stood among the adverse reactions and in no warnings section. | Text for professionals PROZAC (fluoxetine capsules) for oral use: Full Prescribing InformationProzac capsules ("Pulvules") 10 mg, 20 mg and 40 mg, Dista Products Company · Read in the government's medicines database: DailyMedAlso on record: patients' leaflet, with no such sentence; related document, with such a sentence | Text revisedChecked |
| Canada | Sexual side effects that continue after stopping7 WARNINGS AND PRECAUTIONS · Reproductive Health: Female and Male Potential · Function Sexual side effects that continue after stopping8 ADVERSE REACTIONS · 8.2 Clinical Trial Adverse Reactions · Male and Female Sexual Dysfunction with SSRIs The same text also says8 ADVERSE REACTIONS · 8.2 Clinical Trial Adverse Reactions · Male and Female Sexual Dysfunction with SSRIs An official list of medicines we read shows the originator product as cancelled, revoked or archived. This is the text of another product, the one named in this row. This text names sexual side effects in several places that this row does not show. Together those passages are too long to reproduce here. The document link in this row opens the text. That they are not shown says nothing about how common these side effects are. | Text for professionals PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION INFORMATION: APO-FLUOXETINE, Fluoxetine Capsules, Fluoxetine Oral SolutionAPO-FLUOXETINE capsules 10 mg and 20 mg and oral solution 20 mg/5 mL, Apotex Inc. · Read in the regulator's own database: Drug Product DatabaseAlso on record: patients' leaflet, with such a sentence; 2 related documents, with such a sentence | Text revisedChecked |
| Australia | Sexual side effects that continue after stoppingSection 4.4 · Sexual dysfunctionSection 4.4 of Australia's product information for APO-Fluoxetine has a warning headed sexual dysfunction. It says there are reports of sexual dysfunction that lasted a long time, with symptoms going on after SSRIs or SNRIs were stopped.Summarised, not quoted, because of the TGA's access terms. Sexual side effects that continue after stoppingSection 4.8 · Urogenital System · UncommonIn section 4.8, the list of side effects of the urogenital system has sexual dysfunction among the uncommon ones, and adds in brackets that it occasionally persists after treatment is stopped.Summarised, not quoted, because of the TGA's access terms. The regulator's site asks readers to accept its terms before it shows this text. The originator product is not in the list we read. This is another product from that list. | Text for professionals AUSTRALIAN PRODUCT INFORMATION APO-FLUOXETINE (FLUOXETINE HYDROCHLORIDE)APO-FLUOXETINE, Arrotex Pharmaceuticals Pty Ltd · Read in the regulator's own database: TGA eBSAlso on record: patients' leaflet, with such a sentence | Text revisedChecked |
| New Zealand | Sexual side effects, as listed4.8 Undesirable effects · b. Adverse reactions from clinical trials · Nervous system disorders · Common Sexual side effects that continue after stopping4.8 Undesirable effects · b. Adverse reactions from clinical trials · Reproductive system and breast disorders The same text also says4.8 Undesirable effects · b. Adverse reactions from clinical trials The originator product is not in the list we read. This is another product from that list. This sentence stands in the list of adverse reactions. The warnings section of this text has no entry on sexual function. A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals New Zealand Data Sheet, Arrow - FluoxetineArrow - Fluoxetine 20 mg capsules, Teva Pharma (New Zealand) Limited · Read in the regulator's own database: MedsafeAlso on record: 1 more text for professionals, with such a sentence; 2 patients' leaflets, with such a sentence | Text revisedChecked |
| Germany | Sexual side effects that continue after stopping4.4 Besondere Warnhinweise und Vorsichtsmaßnahmen für die Anwendung · Sexuelle Funktionsstörung Sexual side effects, as listed4.8 Nebenwirkungen · Psychiatrische Erkrankungen · Häufig Sexual side effects, as listed4.8 Nebenwirkungen · Psychiatrische Erkrankungen · Gelegentlich Sexual side effects, as listed4.8 Nebenwirkungen · Erkrankungen der Geschlechtsorgane und der Brustdrüse · Häufig Sexual side effects, as listed4.8 Nebenwirkungen · Erkrankungen der Geschlechtsorgane und der Brustdrüse · Gelegentlich Sexual side effects that continue after stopping4.8 Nebenwirkungen · Tabellarische Zusammenfassung der Nebenwirkungen · Fußnote 16 Sexual side effects, as listed4.8 Nebenwirkungen · Erkrankungen der Geschlechtsorgane und der Brustdrüse · Selten The same text also says4.8 Nebenwirkungen · Zusammenfassung des Sicherheitsprofils Sexual side effects, as listed4.8 Nebenwirkungen · Kinder und Jugendliche This is the holder's own copy. The regulator's database asks visitors to accept its terms first, which we did not do. The originator product's text could not be opened. This is the text of another product, the one named in this row. A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals FachinformationFluoxetin-ratiopharm® 20 mg Hartkapseln, ratiopharm GmbH · Read on the holder's own site: ratiopharm GmbHAlso on record: 1 more text for professionals, could not be opened; patients' leaflet, with such a sentence; patients' leaflet, could not be opened; related document, with such a sentence | Text revisedChecked |
| France | Sexual side effects that continue after stopping4.4. Mises en garde spéciales et précautions d'emploi · Dysfonction sexuelle Sexual side effects, as listed4.8. Effets indésirables · Affections psychiatriques · Fréquent Sexual side effects, as listed4.8. Effets indésirables · Affections psychiatriques · Peu fréquent Sexual side effects, as listed4.8. Effets indésirables · Affections des organes de reproduction et du sein · Fréquent Sexual side effects, as listed4.8. Effets indésirables · Affections des organes de reproduction et du sein · Peu fréquent Sexual side effects that continue after stopping4.8. Effets indésirables · b. Tableau récapitulatif des effets indésirables · note 16 Sexual side effects, as listed4.8. Effets indésirables · Affections des organes de reproduction et du sein · Rare The same text also says4.8. Effets indésirables · a. Résumé du profil de sécurité Sexual side effects, as listed4.8. Effets indésirables · d. Population pédiatrique The text itself prints no date of revision. An official list of medicines we read shows this product as discontinued or no longer marketed, and the text in this row is still this product's own. Texts for other products in this country do not all say the same. The ones we read are on the full record. A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals Résumé des Caractéristiques du ProduitPROZAC 20 mg, gélule, LILLY France · Read in the government's medicines database: Base de données publique des médicamentsAlso on record: 1 more text for professionals, with such a sentence; 2 patients' leaflets, with such a sentence | Updated by the regulatorChecked |
| Italy | Sexual side effects that continue after stopping4.4 Avvertenze speciali e precauzioni di impiego · Disfunzione sessuale Sexual side effects, as listed4.8 Effetti indesiderati · b. Tabella riassuntiva delle reazioni avverse · Disturbi psichiatrici · Comune Sexual side effects, as listed4.8 Effetti indesiderati · b. Tabella riassuntiva delle reazioni avverse · Disturbi psichiatrici · Non comune Sexual side effects, as listed4.8 Effetti indesiderati · b. Tabella riassuntiva delle reazioni avverse · Patologie dell'apparato riproduttivo e della mammella · Comune Sexual side effects, as listed4.8 Effetti indesiderati · b. Tabella riassuntiva delle reazioni avverse · Patologie dell'apparato riproduttivo e della mammella · Non comune Sexual side effects that continue after stopping4.8 Effetti indesiderati · b. Tabella riassuntiva delle reazioni avverse · nota 16 Sexual side effects, as listed4.8 Effetti indesiderati · b. Tabella riassuntiva delle reazioni avverse · Patologie dell'apparato riproduttivo e della mammella · Raro The same text also says4.8 Effetti indesiderati · a. Sommario del profilo di sicurezza Sexual side effects, as listed4.8 Effetti indesiderati · d. Popolazione pediatrica (vedere paragrafi 4.4 e 5.1) The text itself prints no date of revision. An official list of medicines we read shows this product as discontinued or no longer marketed, and the text in this row is still this product's own. Texts for other products in this country do not all say the same. The ones we read are on the full record. A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals Riassunto delle caratteristiche del prodottoProzac 20 mg capsule rigide, Eli Lilly Italia S.p.A. · Read in the regulator's own database: Banca Dati FarmaciAlso on record: 1 more text for professionals, with such a sentence; 2 patients' leaflets, with such a sentence | Made available by the regulatorChecked |
| Spain | Sexual side effects that continue after stopping4.4. Advertencias y precauciones especiales de empleo · Disfunción sexual Sexual side effects, as listed4.8. Reacciones adversas · Resumen tabulado de reacciones adversas · Trastornos psiquiátricos · Frecuentes Sexual side effects, as listed4.8. Reacciones adversas · Resumen tabulado de reacciones adversas · Trastornos psiquiátricos · Poco frecuentes Sexual side effects, as listed4.8. Reacciones adversas · Resumen tabulado de reacciones adversas · Trastornos del aparato reproductor y de la mama · Frecuentes Sexual side effects, as listed4.8. Reacciones adversas · Resumen tabulado de reacciones adversas · Trastornos del aparato reproductor y de la mama · Poco frecuentes Sexual side effects, as listed4.8. Reacciones adversas · Resumen tabulado de reacciones adversas · Trastornos del aparato reproductor y de la mama · Raras The same text also says4.8. Reacciones adversas · Resumen del perfil de seguridad Sexual side effects, as listed4.8. Reacciones adversas · Población pediátrica (ver secciones 4.4 y 5.1) An official list of medicines we read shows the originator product as cancelled, revoked or archived. This is the text of another product, the one named in this row. Texts for other products in this country do not all say the same. We searched them for sentences about sexual side effects continuing after stopping and did not read them whole. This row shows the product named, and no other. Spelling and punctuation are the document's own. A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals Ficha técnicafluoxetina cinfa 20 mg cápsulas duras EFG, Laboratorios Cinfa, S.A. · Read in the regulator's own database: CIMAAlso on record: patients' leaflet, with such a sentence; related document, with such a sentence | Text revisedChecked |
| Brazil | Sexual side effects, as listed9. REAÇÕES ADVERSAS · Reação comum (> 1/100 e < 1/10): Sexual side effects, as listed9. REAÇÕES ADVERSAS · Reação comum (> 1/100 e < 1/10): Sexual side effects, as listed9. REAÇÕES ADVERSAS · Reação comum (> 1/100 e < 1/10): Sexual side effects, as listed9. REAÇÕES ADVERSAS · Reação incomum (> 1/1.000 e <1/100): Sexual side effects, as listed9. REAÇÕES ADVERSAS · Reação incomum (> 1/1.000 e <1/100): Sexual side effects, as listed9. REAÇÕES ADVERSAS · Relatos pós-comercialização: Sexual side effects that continue after stopping9. REAÇÕES ADVERSAS · Relatos pós-comercialização: This is the holder's own copy. The regulator's database refused our requests (it blocks by country; we asked from Denmark). The originator product's text could not be opened. This is the text of another product, the one named in this row. | Text for professionals Fluoxetin (cloridrato de fluoxetina): bula para o profissional de saúdeFluoxetin cápsula dura 20 mg, Cristália Produtos Químicos Farmacêuticos Ltda. · Read on the holder's own site: Cristália Produtos Químicos Farmacêuticos Ltda.Also on record: 1 more text for professionals, could not be opened; patients' leaflet, with such a sentence; patients' leaflet, could not be opened | The text prints no dateChecked |
| India | We could not open this text on 14 October 2026: this regulator publishes no database of such texts. This says nothing about what the text contains. | Text for professionalsWe tried: cdsco.gov.in/opencms/opencms/en/Notifications/Prescribing-Information/ | Tried |
Brand names
These are the brand names of fluoxetine we saw in the official lists, compendia and regulators' pages we opened on or after 14 October 2026. A country may have more.
- Prozac
- United States, France, Italy
- Olena
- United Kingdom
- Prozep
- United Kingdom
- Fluox
- New Zealand
- Fluoxeren
- Italy
- Xeredien
- Italy
- Luramon
- Spain
- Daforin
- Brazil
- Fluoxetin
- Brazil
- Fluxene
- Brazil
- Prozen
- Brazil
- Verotina
- Brazil
- Zyfloxin
- Brazil
What is not known
- No reliable figure exists for how often PSSD happens. (source)
- One study of health records gives an estimate for men, counted through prescriptions for erection medicines. (source)
- It is not known how many people fully recover. (source)
- None of the product texts we read says how long the sexual dysfunction can last. (source)
Code and reporting
In a report to a medicines regulator, the term is Post-SSRI sexual dysfunction (MedDRA code 10086208). Where to report, country by country
Every row in this table was checked on or after . To quote this record, name SIDEfxHUB and give this page's address. All medicines and countries · The whole record as a file: JSON · CSV · How these texts are checked
You may reuse this record under CC BY 4.0 if you credit SIDEfxHUB and give this page's address. The licence covers our compilation, not the texts quoted in it, in the original or in our translation, and not the article above.