The side effects
that never stopped
For some people, hair-loss and antidepressant medicines leave sexual, physical, cognitive and emotional symptoms that never go away. It is called Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction, and we fund the research to end it.
Our WhatsApp Peer Support Groups
Four small, private groups for people living with PFS and PSSD.
PFS/PSSD Group
Benelux, France & Italy
PFS/PSSD Group
Scandinavia
PFS/PSSD Group
United Kingdom
PFS/PSSD Group
US & Canada
The groups are for people on our registry — we’ll show you how in a moment.
Three medicines.
The same story.
Finasteride for hair loss. Isotretinoin for acne. SSRIs for depression. Different drugs, one pattern — and for some people it does not end when the prescription does.
A routine prescription
Ordinary problems, ordinary drugs. Tens of millions of prescriptions a year.
Called rare and reversible
The labels said side effects were uncommon and would lift on stopping. Patients and doctors believed them.
They stopped. It didn’t.
Sexual, physical, cognitive, emotional. Still there years after the last dose.
Recognition is catching up
Now documented by the FDA and EMA. Still not taught in medical school — and closing that gap is our work.
Post Finasteride Syndrome
Prescribed for male pattern hair loss and enlarged prostate. A minority of patients report sexual, cognitive and emotional symptoms that persist after stopping the medication.
Learn more →PSSD
Among the world's most prescribed antidepressants. Some patients experience persistent sexual dysfunction and emotional blunting that continues after treatment ends.
Learn more →Post-Accutane Syndrome
Prescribed for severe acne. Some patients report sexual, cognitive and emotional symptoms that continue long after the course of treatment is completed.
Learn more →Where the answers
are coming from
At the University of Milan, Professor Roberto Melcangi’s team is uncovering the biology behind PFS and PSSD — the most thorough programme ever run on these conditions, and the closest anyone has come to a treatment.
“We are no longer in the dark. The evidence is strong — and the next step is human clinical trials.”
— Prof. Roberto Melcangi
News About PFS & PSSD
Good Morning Britain: Robb Dixon Speaks Out About Post-Finasteride Syndrome
They Wanted a Quick Fix for Hair Loss
What CBC/Radio-Canada Uncovered About Finasteride
Hemmeligheden bag Propecia (Finasterid)
Tusindvis af unge mænd tager Propecia (Finasterid) uden at kende de alvorlige bivirkninger. Hjælp med at sætte fokus på risiciene.
Could PFS and POIS Be Linked?
Could Post-Finasteride Syndrome (PFS) and Post-Orgasmic Illness Syndrome (POIS) Be Linked? Learn more here.
Post-Finasteride Syndrome and Reddit
Reddit has become a vital resource for individuals navigating the complexities of Post-Finasteride Syndrome. Learn more here.
About SIDEfxHUB
Welcome to SIDEfxHUB, a charity dedicated to improving the lives of those impacted by PSSD and PFS. We believe in the power of collective action and are committed to connecting communities to amplify their voices. Our mission is to provide a platform for shared fundraising, support credible research, and enhance patient support through various initiatives.
Join us in our efforts to make a meaningful difference. Whether through donating, participating in our registry, or staying informed with our updates, your involvement is invaluable in moving our cause forward.
Learn more about us →Current Initiatives
WhatsApp Peer Support Groups
Join our peer support WhatsApp groups to connect with others who understand what you are going through. Whether you are dealing with PFS, PSSD, or other medication-related challenges, our supportive community is here to help. Share experiences, ask questions, and find comfort among peers. Join us on WhatsApp today.
PSSD & PFS Registry
The PSSD & PFS Registry links individuals with specific conditions to researchers conducting relevant studies. By joining, you aid in advancing medical research while ensuring your privacy and informed consent. Contribute to the development of new treatments by registering today. Join the registry.
Scientific Medical Research
We are committed to supporting those affected by PFS and PSSD, conditions caused by adverse medication effects. Our mission is to advance research and provide vital support. By working with leading researchers, we aim to find effective treatments and raise awareness. Your support is essential. Donate now.
Join the Registry
Help build the world's largest patient database for PFS and PSSD. Your participation drives research and recognition.
Why join?
Your data directly supports the Milano Project and other research efforts.
Receive updates on research breakthroughs and community initiatives.
Help researchers and regulators understand how many people these conditions affect worldwide.
"For years, I felt like my struggles were invisible. A united registry is the first step toward being truly seen."
— PSSD Patient, GermanyJoin the registry
It takes about 3 minutes, and you can stay anonymous.
- Open to anyone affected by PFS, PAS or PSSD
- Stored securely, never shared without your consent
- Remove your data at any time, no questions asked
Secure · GDPR-compliant · UK charity 1203385