Supporting Patients
Living With PFS, PAS & PSSD
SIDEfxHUB is a UK-registered charity supporting patients affected by Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction through research, advocacy, and community.
Join Our WhatsApp Peer Support Groups
Our groups are currently active in the following regions: UK, US & Canada, Benelux/France/Italy and Scandinavia.
Three medicines. One shared patient experience.
Documented in peer-reviewed research and recognised by the FDA and EMA — yet still widely under-recognised in everyday clinical practice.
A routine prescription
Hair loss. Anxiety. Acne. Patients went to their doctors for common conditions and were prescribed FDA-approved medications taken by tens of millions worldwide.
Side effects described as rare and reversible
Product labelling described side effects as uncommon and reversible on discontinuation. Patients and prescribers alike understood them to be temporary.
They stopped the medication. The symptoms didn't stop.
Persistent sexual dysfunction. Cognitive difficulties. Emotional blunting. For some patients the symptoms continued long after the medication was discontinued.
Recognition is still catching up
Labels have since been updated and research is under way. But these conditions remain uncommon and underreported, and are not yet a routine part of medical training — which is why we work alongside clinicians and researchers to close that gap.
Post Finasteride Syndrome
Prescribed for male pattern hair loss and enlarged prostate. A minority of patients report sexual, cognitive and emotional symptoms that persist after stopping the medication.
Learn more →PSSD
Among the world's most prescribed antidepressants. Some patients experience persistent sexual dysfunction and emotional blunting that continues after treatment ends.
Learn more →Post-Accutane Syndrome
Prescribed for severe acne. Some patients report sexual, cognitive and emotional symptoms that continue long after the course of treatment is completed.
Learn more →Donate to PFS & PSSD Research
Support ongoing research into PFS & PSSD. As a neutral charity, we facilitate direct donations to research studies and provide links to other relevant websites, where appropriate. Thank you for your consideration.
PFS Foundation
Support the Milano Project, led by Dr. Melcangi, aiming to advance the understanding of PFS:
- Explore neurological and hormonal causes of PFS.
- Investigate changes in brain function and gut health.
- Identify potential biomarkers for diagnosis.
- Study steroid imbalances caused by finasteride.
- Lay the groundwork for future treatments and trials.
Goal: Build scientific understanding and pave the way for therapies.
PSSD Network
Contribute to the Milano Project, led by Dr. Melcangi:
- Explores neurological and hormonal causes of PSSD.
- Investigates brain function and gut health.
- Studies steroid imbalances from finasteride use.
- Identifies potential biomarkers for diagnosis.
- Lays groundwork for future treatments and trials.
Goal: Advance scientific understanding of PSSD.
RxISK
Support research into enduring sexual dysfunctions:
- Investigates PSSD through nerve imaging and biomarkers.
- Tests light therapy for sexual function recovery.
- Explores links between SSRIs and p63 protein changes.
- Tracks outcomes from anaesthetics and trial medications.
- Offers the $100K RxISK Prize for treatment breakthroughs.
Goal: Identify causes and potential treatments for PSSD.
News About PFS & PSSD
Good Morning Britain: Robb Dixon Speaks Out About Post-Finasteride Syndrome
They Wanted a Quick Fix for Hair Loss
What CBC/Radio-Canada Uncovered About Finasteride
Hemmeligheden bag Propecia (Finasterid)
Tusindvis af unge mænd tager Propecia (Finasterid) uden at kende de alvorlige bivirkninger. Hjælp med at sætte fokus på risiciene.
Could PFS and POIS Be Linked?
Could Post-Finasteride Syndrome (PFS) and Post-Orgasmic Illness Syndrome (POIS) Be Linked? Learn more here.
Post-Finasteride Syndrome and Reddit
Reddit has become a vital resource for individuals navigating the complexities of Post-Finasteride Syndrome. Learn more here.
About SIDEfxHUB
Welcome to SIDEfxHUB, a charity dedicated to improving the lives of those impacted by PSSD and PFS. We believe in the power of collective action and are committed to connecting communities to amplify their voices. Our mission is to provide a platform for shared fundraising, support credible research, and enhance patient support through various initiatives.
Join us in our efforts to make a meaningful difference. Whether through donating, participating in our registry, or staying informed with our updates, your involvement is invaluable in moving our cause forward.
Learn more about us →Current Initiatives
WhatsApp Peer Support Groups
Join our peer support WhatsApp groups to connect with others who understand what you are going through. Whether you are dealing with PFS, PSSD, or other medication-related challenges, our supportive community is here to help. Share experiences, ask questions, and find comfort among peers. Join us on WhatsApp today.
PSSD & PFS Registry
The PSSD & PFS Registry links individuals with specific conditions to researchers conducting relevant studies. By joining, you aid in advancing medical research while ensuring your privacy and informed consent. Contribute to the development of new treatments by registering today. Join the registry.
Scientific Medical Research
We are committed to supporting those affected by PFS and PSSD, conditions caused by adverse medication effects. Our mission is to advance research and provide vital support. By working with leading researchers, we aim to find effective treatments and raise awareness. Your support is essential. Donate now.
Join the Registry
Help build the world's largest patient database for PFS and PSSD. Your participation drives research and recognition.
Why join?
Your data directly supports the Milano Project and other research efforts.
Receive updates on research breakthroughs and community initiatives.
Help researchers and regulators understand how many people these conditions affect worldwide.
"For years, I felt like my struggles were invisible. A united registry is the first step toward being truly seen."
— PSSD Patient, GermanyJoin the registry
It takes about 3 minutes, and you can stay anonymous.
- Open to anyone affected by PFS, PAS or PSSD
- Stored securely, never shared without your consent
- Remove your data at any time, no questions asked
Secure · GDPR-compliant · UK charity 1203385