Citalopram side effects: can they last?
Most citalopram side effects ease. Sexual problems are common, and the UK leaflet warns they have sometimes continued after stopping. This is called PSSD.
SIDEfxHUB is a patient charity. We are not health professionals, and this does not replace medical advice. Don't start, stop or change any medicine because of what you read here. Talk to your doctor first.
If you are in crisis:116 123 Samaritans (UK)988 Lifeline (US)Find a helpline

Citalopram’s common side effects include feeling sick, sweating, poor sleep and sexual problems, such as a low sex drive or trouble reaching orgasm. Most ease after a couple of weeks, but the UK leaflet warns sexual problems have sometimes continued after stopping, a condition called post-SSRI sexual dysfunction (PSSD).
PSSD is more than sexual problems. Its core is a lasting change in genital sensation, often numbness, and the 2022 diagnostic criteria also describe emotional numbing, problems with thinking and changes in other senses.
The NHS page on citalopram doesn’t mention that warning. Citalopram’s heart risk was measured to the millisecond, but no reliable figure exists for how often its sexual side effects outlast the tablets.
The story in 3 lines
- Sexual problems, such as a low sex drive, are a common side effect of citalopram (NHS).
- The UK leaflet warns they have sometimes continued after stopping (leaflet).
- No reliable figure exists for how often this happens after citalopram. Patients call it PSSD (Healy and Mangin, 2024).
Press: contact@sidefxhub.com
Roy Whaley took citalopram briefly when he was 22. Sixteen years later, he told The New York Times, his penis still felt almost as if it had been injected with a local anaesthetic. His sex drive had gone, and orgasms brought no pleasure.
Over the years, doctors kept suggesting the problem was psychological. One note in his records, from 2009, called citalopram “exceptionally unlikely” to be the cause. “We feel very neglected,” he said.
What are the most common side effects of citalopram?
The UK leaflet lists these as the most common:
- feeling sick
- sweating and a dry mouth
- headaches
- sleeping badly, or feeling sleepy
- feeling weak
The leaflet says these are often mild. Some can also be signs of the illness itself, and may fade as you get better.
The leaflet lists sexual problems as common, too. In men that means a lower sex drive and trouble with ejaculation and erections. In women it means a lower sex drive and not being able to reach orgasm.
How common are sexual side effects on citalopram?
They’re common. Studies that ask about sex directly tend to find more of them. In one large US study, everyone took citalopram and filled in a questionnaire that asked about sex.
About half reported a lower sex drive. There was no placebo group, though, and depression can dull desire too.
The trials behind the US label recorded far fewer than that. The label itself says its figures “may underestimate” the real rate, because patients and doctors may be reluctant to talk about sex.
Whether these problems can outlast the tablets is a different question. If you only have 90 seconds, watch Joanna Moncrieff, a professor of psychiatry at University College London. She isn’t talking about citalopram alone, but she explains what people describe after stopping antidepressants in general.
Can citalopram side effects last after stopping?
The UK leaflet says the sexual ones sometimes have: “In some cases, these symptoms have continued after stopping treatment.” In 2019 the EU medicines regulator asked for that warning on ten SSRI and SNRI antidepressants, citalopram among them.
Patients and researchers call this PSSD. Under the 2022 criteria, its key sign is a lasting change in genital sensation, like Roy’s numbness. These are proposed criteria, written by researchers and clinicians, and not yet an official diagnosis.
For some people it has lasted years after stopping. Nobody knows yet who will be affected, or whether it will ease.
Andy was 23 when he was prescribed citalopram. Watch his interview with Moral Medicine to hear what it’s like when it doesn’t ease: he describes symptoms that have lasted more than 13 years and go far beyond sex. It’s 27 minutes, so start where you like.
Does citalopram affect your heart?
It can. The UK prescribing information says citalopram lengthens the QT interval, the time the heart takes to recharge between beats, and more so at higher doses.
If that interval runs too long, a rare but life-threatening rhythm becomes more likely. The leaflet says a fast, irregular heartbeat or fainting needs medical advice at once.
A heart study measured the effect at different doses. Then, in 2011, the UK medicines regulator capped the dose at 40 mg a day, or 20 mg for people over 65.
As far as we can find, nobody has run a study like that for sexual problems after stopping. We think it needs one.
What can I do if I have side effects?
These medicines help many people. If you have side effects, that’s a decision for you and your prescriber. Don’t stop suddenly: the leaflet says stopping quickly can bring dizziness and sleep problems, and the dose is usually lowered gradually.
If sexual problems, numbness or feeling flat haven’t lifted after stopping, tell your GP. Many people say it took time to be taken seriously. Write the basics down first: “Citalopram 20 mg from January 2023, last tablet March 2024. Genitals numb since April.”
Three questions for your GP
- Could citalopram explain what I still feel, even after stopping?
- What else should we rule out?
- Can this go on my record as a suspected side effect?
You could start with: “The leaflet says sexual problems have sometimes continued after stopping. I think that's happening to me.”
Bring the leaflet line. You can report it without a doctor agreeing.
Report it: it helps everyone
A doctor’s note helps you. A report to the medicines regulator helps everyone else: it is how patterns get noticed.
- No proof needed. A suspicion is enough, even years after stopping.
- Where: the Yellow Card scheme in the UK, MedWatch in the US.
- Use the right words. If symptoms continued after stopping, write Post-SSRI sexual dysfunction (MedDRA 10086208).
Our reporting guide walks you through it
Do citalopram side effects go away? Most ease after a couple of weeks, says the NHS, as your body gets used to the medicine. Sexual problems are different: the leaflet warns they have sometimes continued after stopping. Nobody knows how many people with PSSD fully recover: the researchers David Healy and Dee Mangin wrote in 2024 that this “has never been properly investigated”.
Can citalopram make you feel emotionally numb? It can: the UK leaflet lists “reduced emotions, indifference” among its common side effects. Many patients call this emotional blunting. The 2022 criteria for PSSD list emotional numbing as a possible feature after stopping, too.
Is citalopram the same as escitalopram? Not quite. Citalopram (Cipramil, Celexa) is an equal mix of two mirror-image molecules, and escitalopram (Lexapro, Cipralex) is one of them on its own. The 2019 EU warning about sexual problems after stopping covers both, and our Lexapro article has more.
Roy’s doctor believes him now, he said, partly because of that warning from European regulators. If your symptoms haven’t lifted, take that warning to your own doctor.
Sources
- Cipramil 20 mg film-coated tablets, patient information leaflet, last revised January 2025. Electronic Medicines Compendium. Sections 2 (sexual problems after stopping), 3 (doses and stopping) and 4 (side effects).
- Cipramil 20 mg film-coated tablets, summary of product characteristics, text revised November 2023. Section 4.4 (QT prolongation and sexual dysfunction) and section 5.1 (QTc study in healthy volunteers).
- NHS, Side effects of citalopram, last reviewed 26 June 2026.
- Celexa (citalopram), US prescribing information, revised October 2023. DailyMed. Section 6.1, on sexual dysfunction: figures “may underestimate their actual incidence”.
- MHRA, Citalopram and escitalopram: QT interval prolongation, Drug Safety Update, December 2011.
- European Medicines Agency, PRAC, new product information wording, signals adopted at the 13-16 May 2019 meeting, EMA/PRAC/265221/2019. The wording is for ten medicines: citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, desvenlafaxine, duloxetine, milnacipran and venlafaxine.
- Perlis RH, Laje G, Smoller JW and colleagues. Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients. Neuropsychopharmacology 2009;34(7):1819-28. STAR*D: 799 of 1,473 participants treated openly with citalopram for up to 14 weeks reported decreased libido; no placebo group.
- Healy D, Bahrick A, Bak M and colleagues. Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin. Int J Risk Saf Med 2022;33(1):65-76.
- Healy D, Mangin D. Post-SSRI sexual dysfunction: barriers to quantifying incidence and prevalence. Epidemiol Psychiatr Sci 2024;33:e40.
- The New York Times, After antidepressants, a loss of sexuality, by Azeen Ghorayshi, 9 November 2023. Subscription required.
- Videos: Moral Medicine, Andy’s 13 year battle with PSSD, 5 October 2024, 27 minutes; PSSD Network, Professor Joanna Moncrieff on PSSD, June 2026, 1:29.
- Picture: Citalopram20-40.jpg by Elbreapoly, public domain, via Wikimedia Commons; converted to WebP.
This information does not replace medical advice. Talk to your doctor before you make any decision about your treatment.
640+ people have joined the registry.
Join them, then report your side effects.
Free. Sign up takes 2 minutes.
Citalopram: what the official texts say, country by country
For the SSRI antidepressant citalopram (Celexa, Cipramil), the product information we read in the United Kingdom says there have been reports of long-lasting sexual dysfunction where symptoms continued after SSRIs or SNRIs were stopped. This is known as post-SSRI sexual dysfunction (PSSD). The EU medicines regulator set the wording of this warning in 2019 for ten medicines, citalopram among them, and a government answer in Parliament says UK product information for all SSRIs was updated in 2019 to carry it.
This is a record of what each text says and of the date it prints. A text is quoted in its own words, or summarised where the row says so. It is not a comparison of countries. All medicines and countries
Citalopram: the official texts, country by country (32 texts read)
| Country or region | What the text says | Document | Dates |
|---|---|---|---|
| United Kingdom | Sexual side effects that continue after stopping4.4 Special warnings and precautions for use · Sexual dysfunction Sexual side effects, as listed4.8 Undesirable effects · Psychiatric disorders · Common Sexual side effects, as listed4.8 Undesirable effects · Psychiatric disorders · Uncommon Sexual side effects, as listed4.8 Undesirable effects · Reproductive system and breast disorders · Common Sexual side effects, as listed4.8 Undesirable effects · Reproductive system and breast disorders · Not known The same text also says4.8 Undesirable effects A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals Summary of Product Characteristics (SmPC): Cipramil 20 mg film-coated tabletsCipramil 20 mg film-coated tablets, Lundbeck Limited · Read in a compendium of product information: emcAlso on record: patients' leaflet, with such a sentence; 3 related documents, with such a sentence | Text revisedChecked |
| European Union | Sexual side effects that continue after stopping3. Serotonin and noradrenaline reuptake inhibitors (SNRI); selective serotonin reuptake inhibitors (SSRI) – Persistent sexual dysfunction after drug withdrawal (EPITT no 19277) · Summary of product characteristics · 4.4. Special warnings and precautions for use · Sexual dysfunction Sexual side effects that continue after stopping3. Serotonin and noradrenaline reuptake inhibitors (SNRI); selective serotonin reuptake inhibitors (SSRI) – Persistent sexual dysfunction after drug withdrawal (EPITT no 19277) · Package leaflet · 2. What you need to know before you take [Invented name] · Warnings and precautions The wording is for ten medicines: citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, desvenlafaxine, duloxetine, milnacipran and venlafaxine. This is wording for national product texts. There is no single EU product text for this medicine. | Document from the regulator New product information wording – Extracts from PRAC recommendations on signals. Adopted at the 13-16 May 2019 PRACRead on the regulator's site: European Medicines AgencyAlso on record: 1 more related document, with such a sentence | PublishedChecked |
| United States | Sexual side effects, as listed5 WARNINGS AND PRECAUTIONS · 5.10 Sexual Dysfunction The same text also says5 WARNINGS AND PRECAUTIONS · 5.10 Sexual Dysfunction This text has no sentence about sexual side effects continuing after the medicine is stopped. This text names sexual side effects in several places that this row does not show. Together those passages are too long to reproduce here. The document link in this row opens the text. That they are not shown says nothing about how common these side effects are. On 14 October 2026 we searched the labels in openFDA, the FDA's open database. A sentence about sexual dysfunction continuing after stopping stood on none of the 320 labels in that database that name citalopram. | Text for professionals CELEXA (citalopram) tablets, for oral use: Full Prescribing InformationCelexa film-coated tablets 10 mg, 20 mg and 40 mg, Allergan, Inc. · Read in the government's medicines database: DailyMedAlso on record: patients' leaflet, with no such sentence | Text revisedChecked |
| Canada | Sexual side effects that continue after stopping7. Warnings and Precautions · Reproductive Health · Function Sexual side effects that continue after stopping8. Adverse Reactions · 8.2. Clinical Trial Adverse Reactions · Male and Female Sexual Dysfunction with SSRIs The same text also says8. Adverse Reactions · 8.2. Clinical Trial Adverse Reactions · Male and Female Sexual Dysfunction with SSRIs This text names sexual side effects in several places that this row does not show. Together those passages are too long to reproduce here. The document link in this row opens the text. That they are not shown says nothing about how common these side effects are. | Text for professionals Product Monograph Including Patient Medication Information: CELEXA®, citalopram hydrobromide, TabletsCelexa tablets 10 mg, 20 mg and 40 mg, Lundbeck Canada Inc. · Read in the regulator's own database: Drug Product DatabaseAlso on record: patients' leaflet, with such a sentence; 2 related documents, with such a sentence | Text approvedChecked |
| Australia | Sexual side effects that continue after stopping4.4 Special warnings and precautions for use · Sexual dysfunctionSection 4.4 of Australia's product information for Cipramil has a warning headed sexual dysfunction. It says there are reports of sexual dysfunction that lasted a long time, with symptoms going on after SSRIs or SNRIs were stopped.Summarised, not quoted, because of the TGA's access terms. The regulator's site asks readers to accept its terms before it shows this text. | Text for professionals AUSTRALIAN PRODUCT INFORMATION – CIPRAMIL (CITALOPRAM HYDROBROMIDE) FILM-COATED TABLETSCIPRAMIL, Lundbeck Australia Pty Ltd · Read in the regulator's own database: TGA eBSAlso on record: patients' leaflet, with such a sentence | Text revisedChecked |
| New Zealand | Sexual side effects that continue after stopping4.4 Special warnings and precautions for use · Warnings · Sexual dysfunction This text names sexual side effects in several places that this row does not show. Together those passages are too long to reproduce here. The document link in this row opens the text. That they are not shown says nothing about how common these side effects are. | Text for professionals New Zealand Data Sheet, CipramilCipramil 20 mg film-coated tablets, Pharmacy Retailing t/a Healthcare Logistics · Read in the regulator's own database: MedsafeAlso on record: patients' leaflet, with such a sentence; 2 related documents, with such a sentence | Text revisedChecked |
| Germany | Sexual side effects that continue after stopping2. Was sollten Sie vor der Einnahme von Cipramil beachten? · Warnhinweise und Vorsichtsmaßnahmen Sexual side effects, as listed4. Welche Nebenwirkungen sind möglich? · Häufig (kann bis zu 1 von 10 Behandelten betreffen) Sexual side effects, as listed4. Welche Nebenwirkungen sind möglich? · Nicht bekannt (Häufigkeit auf Grundlage der verfügbaren Daten nicht abschätzbar) The same text also says4. Welche Nebenwirkungen sind möglich? This is the copy in a compendium of product information. The regulator's database asks visitors to accept its terms first, which we did not do. | Patient leaflet Gebrauchsinformation: Information für PatientenCipramil 20 mg, Filmtabletten, Lundbeck GmbH · Read in a compendium of product information: PatientenInfo-ServiceAlso on record: text for professionals, with such a sentence; text for professionals, could not be opened; related document, with such a sentence | Text revisedChecked |
| France | Sexual side effects that continue after stopping4.4. Mises en garde spéciales et précautions d'emploi · Dysfonction sexuelle Sexual side effects, as listed4.8. Effets indésirables · Affections psychiatriques · Fréquent Sexual side effects, as listed4.8. Effets indésirables · Affections des organes de reproduction et du sein · Fréquent Sexual side effects, as listed4.8. Effets indésirables · Affections des organes de reproduction et du sein · Fréquence indéterminée The same text also says4.8. Effets indésirables The text itself prints no date of revision. A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals Résumé des Caractéristiques du ProduitSEROPRAM 20 mg, comprimé pelliculé sécable, LUNDBECK SAS · Read in the government's medicines database: Base de données publique des médicamentsAlso on record: patients' leaflet, with such a sentence | Updated by the regulatorChecked |
| Italy | Sexual side effects that continue after stopping4.4 Avvertenze speciali e precauzioni di impiego · Disfunzione sessuale Sexual side effects, as listed4.8 Effetti indesiderati · Disturbi psichiatrici · Comune Sexual side effects, as listed4.8 Effetti indesiderati · Patologie dell’apparato riproduttivo e della mammella · Comune Sexual side effects, as listed4.8 Effetti indesiderati · Patologie dell’apparato riproduttivo e della mammella · Non nota The same text also says4.8 Effetti indesiderati The text itself prints no date of revision. A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals Riassunto delle caratteristiche del prodottoSeropram compresse rivestite con film, Lundbeck Italia S.p.A. · Read in the regulator's own database: Banca Dati FarmaciAlso on record: patients' leaflet, with such a sentence | Made available by the regulatorChecked |
| Spain | Sexual side effects that continue after stopping4.4. Advertencias y precauciones especiales de empleo · Disfunción sexual Sexual side effects, as listed4.8. Reacciones adversas · Trastornos psiquiátricos · Frecuente Sexual side effects, as listed4.8. Reacciones adversas · Trastornos del aparato reproductor y de la mama · Frecuente Sexual side effects, as listed4.8. Reacciones adversas · Trastornos del aparato reproductor y de la mama · No conocida The same text also says4.8. Reacciones adversas A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals Ficha técnicaSeropram 30 mg comprimidos recubiertos con película, Lundbeck España, SA · Read in the regulator's own database: CIMAAlso on record: patients' leaflet, with such a sentence; related document, with such a sentence | Text revisedChecked |
| Brazil | Sexual side effects, as listed9. REAÇÕES ADVERSAS · Distúrbios psiquiátricos · Comum Sexual side effects, as listed9. REAÇÕES ADVERSAS · Distúrbios do sistema reprodutor e mamas · Comum Sexual side effects, as listed9. REAÇÕES ADVERSAS · Distúrbios do sistema reprodutor e mamas · Desconhecido The same text also says9. REAÇÕES ADVERSAS This text has no sentence about sexual side effects continuing after the medicine is stopped. This is the holder's own copy. The regulator's database refused our requests (it blocks by country; we asked from Denmark). The originator product's text could not be opened. This is the text of another product, the one named in this row. A table cell or list line is shown whole, as the text prints it. Some of them also name side effects that are not sexual. | Text for professionals DENYL® bromidrato de citalopram: bula para o profissional de saúdeDenyl comprimidos revestidos 20 mg, Cristália Produtos Químicos Farmacêuticos Ltda. · Read on the holder's own site: Cristália Produtos Químicos Farmacêuticos Ltda.Also on record: 1 more text for professionals, could not be opened; 2 patients' leaflets, with no such sentence; patients' leaflet, could not be opened | Last change listedChecked |
| India | We could not open this text on 14 October 2026: this regulator publishes no database of such texts. This says nothing about what the text contains. | Text for professionalsWe tried: cdsco.gov.in/opencms/opencms/en/Notifications/Prescribing-Information/ | Tried |
Brand names
These are the brand names of citalopram we saw in the official lists, compendia and regulators' pages we opened on or after 14 October 2026. A country may have more.
- Celexa
- United States, Canada
- CTP 30
- Canada
- Cipramil
- United Kingdom, New Zealand, Germany, Brazil
- Seropram
- France, Italy, Spain
- Celapram
- New Zealand
- Elopram
- Italy
- Frimaind
- Italy
- Ricap
- Italy
- Sintopram
- Italy
- Kaidor
- Italy
- Return
- Italy
- Prisdal
- Spain
- Citalvir
- Spain
- Alcytam
- Brazil
- Città
- Brazil
- Denyl
- Brazil
- Maxapran
- Brazil
- Nypram
- Brazil
- Procimax
- Brazil
What is not known
- No reliable figure exists for how often PSSD happens. (source)
- One study of health records gives an estimate for men, counted through prescriptions for erection medicines. (source)
- It is not known how many people fully recover. (source)
- None of the product texts we read says how long the sexual dysfunction can last. (source)
Code and reporting
In a report to a medicines regulator, the term is Post-SSRI sexual dysfunction (MedDRA code 10086208). Where to report, country by country
Every row in this table was checked on or after . To quote this record, name SIDEfxHUB and give this page's address. All medicines and countries · The whole record as a file: JSON · CSV · How these texts are checked
You may reuse this record under CC BY 4.0 if you credit SIDEfxHUB and give this page's address. The licence covers our compilation, not the texts quoted in it, in the original or in our translation, and not the article above.