The symptoms of PFS indicate physiological disturbances impacting the body, mind, sexuality, behavior, and identity. The syndrome can cause feelings of disconnection, lack of purpose, isolation, social withdrawal, and disinterest in normal activities and relationships. These effects highlight the significance of the hormonal pathways disrupted by 5ARIs, which support the functions of the male reproductive system, brain, skin, eyes, kidneys, liver, heart, bones and muscle sometimes resulting in severe physical disability.
Some medical commentators have attributed the syndrome to low testosterone, ordinary depression, or psychological disorders, calling it persistent side effects, which is unlikely once the drug has left the body.
The syndrome’s impact extends to the partners, friends, and family of those affected. Disabling of sexuality and loss of interest in daily life can jeopardize relationships. Dating and forming new relationships may become challenging, especially if friends and family misunderstand or doubt the syndrome.
