Study Reveals Persistent Penile Vascular Abnormalities and Severe Side Effects in Men After Discontinuing 5ARIs for Hair Loss
This study, conducted by researchers from Baylor College of Medicine and other institutions, investigates the persistent side effects experienced by men who discontinued the use of 5α-reductase inhibitors (5ARIs) for androgenic alopecia (AGA). The study involved 25 men with a history of 5ARI use and 28 controls. Using various self-reported questionnaires and Penile Duplex Doppler Ultrasound (PDDU) assessments, the study found significant differences in the sexual and psychological health of those who had used 5ARIs compared to the control group. Notably, 68% of the 5ARI users exhibited penile vascular abnormalities, and they scored higher on measures of depression and sexual dysfunction. Alarmingly, two participants in the 5ARI group committed suicide during or after the study. The findings suggest that the adverse effects of 5ARIs extend beyond sexual dysfunction, potentially causing long-lasting genitourinary, physical, and psychological harm even after discontinuation of the drug. The study underscores the importance of carefully considering the risks before using 5ARIs for AGA treatment.
Read the full study here: https://pubmed.ncbi.nlm.nih.gov/32676403/
Learn more about PFS & PSSD
What is Post-Finasteride Syndrome?
PFS (Post-Finasteride Syndrome) is a complex and life-altering condition caused by the drug Finasteride (also marketed as Propecia) and other 5ar inhibitors. It affects physical, mental, and sexual health, leaving patients to suffer without adequate support, recognition or treatment.
What is Post-SSRI Sexual Dysfunction?
PSSD (Post-SSRI Sexual Dysfunction) is a serious and debilitating condition associated with the use of selective serotonin reuptake inhibitors (SSRIs) and similar drugs. It affects mental, physical, and sexual well-being, leaving many patients to suffer without sufficient support, recognition, or effective treatment.
