The Similarities Between Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction
The article delves into the persistent and often debilitating side effects of Post-Finasteride Syndrome (PFS) and Post-SSRI Sexual Dysfunction (PSSD). Although these conditions stem from different drugs—finasteride, used for androgenetic alopecia, and SSRIs, commonly prescribed for depression—they exhibit strikingly similar symptoms, including sexual dysfunction, psychological complaints, and sleep disorders.
The authors propose that both PFS and PSSD may share common pathological mechanisms involving neuroactive steroids, neurotransmitters such as serotonin and catecholamines, and the gut-brain axis influenced by gut microbiota. The article emphasizes the critical need for further research to better understand these conditions, develop diagnostic markers, and establish effective treatments. The study suggests that steroid-based therapeutic strategies might offer potential solutions, especially in light of recent findings in animal models where treatments like allopregnanolone showed promise in counteracting some of the adverse effects associated with these conditions.
For a more comprehensive understanding, you can read the full article here.
Learn more about PFS & PSSD
What is Post-Finasteride Syndrome?
PFS (Post-Finasteride Syndrome) is a complex and life-altering condition caused by the drug Finasteride (also marketed as Propecia) and other 5ar inhibitors. It affects physical, mental, and sexual health, leaving patients to suffer without adequate support, recognition or treatment.
What is Post-SSRI Sexual Dysfunction?
PSSD (Post-SSRI Sexual Dysfunction) is a serious and debilitating condition associated with the use of selective serotonin reuptake inhibitors (SSRIs) and similar drugs. It affects mental, physical, and sexual well-being, leaving many patients to suffer without sufficient support, recognition, or effective treatment.
